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Reanzen Co., Ltd announced on March 4, 2022 that it has achieved domestic approval for HA fillers under the REVS brand. 

It is characterized by precisely and evenly processing hyaluronic acid gel particles by applying Reanzen's proprietary MGT (Micro Grinding Technology). Hyaluronic acid filler can be treated stably with a soft injection and precise extrusion force.

The HA filler developed by Reanzen was developed such a way that it could be selected from three lines, mid-light, mid, and pro, depending on the skin condition of the person receiving the treatment, such as wrinkles, and pursued differentiation from existing fillers.

In the HA filler manufacturing process, the crosslinking process is done using a harmful component called BDDE, but the component is removed after the process is completed. Reanzen's HA filler has been recognized for its high safety by removing various harmful substances including BDDE.

According to the company, this is possible because Reanzen's HBCT (Hexagonal Block Cross-linking Technology) technology is applied. The company explains that this is because the structure of the filler enables parallel crosslinking of the main raw material in small block units while maintaining a constant temperature. The unique REVS filler structure contributes to the formation of more HA cross-links and a longer duration by delaying the rate of degradation in the body. As the viscoelasticity is maintained for a long period of time, the volume recovery effect is maximized.

The effectiveness of REVS has been confirmed through confirmatory clinical trials. Changes were measured after the procedure was performed at 4-week intervals for a total of 70 subjects. Stable durability for up to one year has been proven, and satisfaction with the procedure has been highly evaluated not only in the middle-aged group but also in the younger age group.

Reanzen Co., Ltd CEO Kwon Soon-ik said, “With this approval, it became an opportunity to realize one step towards the anti-aging market, which is the dream of all mankind. We will do our best to research and develop products.”